Chemistry English Faculty Faculty & Research

Kim , Jong Goo



  • 링크이동
  • Phone+82.53.785.6536
  • OfficeE2-608
  • LabBE2-621


  • Reaction mechanism
  • Protein structural dynamics
  • Solution-phase reaction dynamics
  • Time-resolved x-ray scattering


Postdoctoral researcher at KAIST
CAREER Research Fellow at Institute for Basic Science (IBS)

Our Researches

The most intuitive approach to unveiling reaction mechanisms is real-time tracking of the three-dimensional structure of molecules involved in a chemical reaction. We utilize time-resolved x-ray scattering to visualize the structural changes of molecules, capturing a dynamic “molecular movie”, which allows us to identify precise reaction pathways and mechanisms. This method is not limited to small molecules but can also be applied to macromolecules such as proteins, enabling real-time tracking of structural changes in proteins during biologically-relevant reactions. Our ultimate goal is to provide fundamental information on the mechanism of various chemical reactions, which can be valuable for optimizing catalytic efficiency and controlling reaction products. Furthermore, by elucidating the correlation between protein structure and function, we can also gain insights into various biological phenomena and diseases caused by abnormal protein interactions.

Representative Publications

2020 “Mapping the emergence of molecular vibrations mediating bond formation”
J. G. Kim, S. Nozawa, H. Kim, E. H. Choi, T. Sato, T. W. Kim, K. H. Kim, H. Ki, J. Kim, M. Choi, Y. Lee, J. Heo, K. Y. Oang, K. Ichiyanagi, R. Fukaya, J. H. Lee, J. Park, I. Eom, S. H. Chun, S. Kim, M. Kim, T. Katayama, T. Togashi, S. Owada, M. Yabashi, S. J. Lee, S. Lee, C. W. Ahn, D.-S. Ahn, J. Moon, S. Choi, J. Kim, T. Joo, J. Kim, S. Adachi, H. Ihee*
Nature 2020, 582, 520
2015 “Direct observation of bond formation in solution with femtosecond X-ray scattering”
K. H. Kim#, J. G. Kim#, S. Nozawa#, T. Sato#, K. Y. Oang, T. W. Kim, H. Ki, J. Jo, S. Park, C. Song, T. Sato, K. Ogawa, T. Togashi, K. Tono, M. Yabashi, T. Ishikawa, J. Kim, R. Ryoo, J. Kim, H. Ihee*, S.-i. Adachi*
Nature 2015, 518, 385
2022 “Determining the charge distribution and the direction of bond cleavage with femtosecond anisotropic x-ray liquidography”
J. Heo#, J. G. Kim#, E. H. Choi, H. Ki, D.-S. Ahn, J. Kim, S. Lee, H. Ihee*
Nature Communications 2022, 13, 522
2021 “Ultrafast coherent motion and helix rearrangement of homodimeric hemoglobin visualized with femtosecond X-ray solution”
Y. Lee#, J. G. Kim#, S. J. Lee, S. Muniyappan, T. W. Kim, H. Ki, H. Kim, J. Jo, S. R. Yun, H. Lee, K. W. Lee, S. O. Kim, M. Cammarata, H. Ihee*
Nature Communications 2021, 12, 3677
2021 “Femtosecond X-ray liquidography visualizes wavepacket trajectories in multidimensional nuclear coordinates for a bimolecular reaction”
J. G. Kim, E. H. Choi, Y. Lee, H. Ihee*
Accounts of Chemical Research, 2021, 54, 1685
2015 “Protein structural dynamics revealed by time-resolved X-ray solution scattering”
J. G. Kim#, T. W. Kim#, J. Kim, H. Ihee*
Accounts of Chemical Research, 2015, 48(8), 2200