Faculty & Research
Chemistry
Jung, ByunghyuckASSOCIATE PROFESSOR
- Website
ASYMMETRIC ORGANIC SYNTHESIS AND DRUG SYNTHESIS
- E-mailbyunghyuck.jung@dgist.ac.kr
- Phone +82.53.785.6625
- OfficeE2-211
- Lab E2-216
RESEARCH AREA
- Catalytic Asymmetric Synthesis
- Synthetic Methodologies
- Synthesis of Natural Products and Drugs
ACADEMIC & CAREER EXPERIENCE
| ACADEMIC | KAIST, Korea |
|---|---|
| Ph. D. | |
| CAREER | Senior Engineer at Samsung Electro-Mechanics |
| Postdoctoral researcher at KAIST | |
| Postdoctoral researcher at Boston College |
Our Researches
Asymmetric Organic Synthesis and Drug Synthesis Laboratory(비대칭 유기합성 및 의약품 합성 연구실)
– Most of drugs, including Remdesivir® as a potential candidate for COVID-19, have chiral carbon-centers and Thalidomide-scandal had brought the importance of stereoselective synthesis of drugs. In this sense, we pursue the development of practical and efficient asymmetric reactions to apply for the lab-scale or bulk-scale synthesis of chiral drugs. To realize that, we focus on 1) the design and the synthesis of novel chiral catalysts, 2) the development of practical reagents, and 3) the development of novel methodology for C-C, C-O, C-N, or C-B bond formations.
– Most of drugs, including Remdesivir® as a potential candidate for COVID-19, have chiral carbon-centers and Thalidomide-scandal had brought the importance of stereoselective synthesis of drugs. In this sense, we pursue the development of practical and efficient asymmetric reactions to apply for the lab-scale or bulk-scale synthesis of chiral drugs. To realize that, we focus on 1) the design and the synthesis of novel chiral catalysts, 2) the development of practical reagents, and 3) the development of novel methodology for C-C, C-O, C-N, or C-B bond formations.
Representative Publications
| 2022 | “Synthesis of Alkynamides through Reaction of Alkyl- or Aryl-Substituted Alkynylaluminums with Isocyanates” |
|---|---|
| Cho, S.; Lee, Y.; Lee, K.; Lee, H.; Lee, Y.; Jung, B. | |
| Org. Biomol. Chem. 2022, 20, 139-151. | |
| 2021 | “Pd-Catalyzed Regio- and Stereoselective sp3 C-H Arylation of Primary Aliphatic Amines: Mechanistic Studies and Synthetic Applications” |
| Ha, H.; Choi, H. J.; Park, H.; Gwon, Y.; Lee, J.; Kwak, J.*; Kim, M.*; Jung, B.* | |
| Eur. J. Org. Chem. 2021, 1136-1145 | |
| 2020 | “Stereoselective Formal Hydroamidation of Si-Substituted Arylacetylenes with DIBAL-H and Isocyanates: Synthesis of (E)- and (Z)-α-Silyl-α,β-Unsaturated Amides” |
| Lee, H.; Cho, S.; Lee, Y.*; Jung, B.* | |
| J. Org. Chem. 2020, 85, 12024-12035. | |
| 2019 | “Synthetic Strategies for (-)-Cannabidiol and Its Structural Analogs” |
| Jung, B.*; Lee, J. K.; Kim, J.; Kang, E. K.; Hans, S. Y.; Lee, H.-Y.; Choi, I. S.* | |
| Chem. Asian. J. 2019, 3749-3762. | |
| 2018 | “Cu(I)-Catalyzed Enantioselective Alkyl 1,4-Additions to (E)-Nitroalkenes and Cyclic Enones with Phosphino-Oxazoline Ligands” |
| Shin, M.; Gu, M.; Lim, S. S.; Kim, M.-J.; Lee, J.-H.; Jin, H.-G.; Jang, Y. H.; Jung, B.* | |
| Eur. J. Org. Chem. 2018, 3122–3130. |