Category: Chemistry

화학과

Categories
Chemistry English Faculty Faculty & Research

Kim , Jong Goo

Faculty & Research


Chemistry

Kim, Jong GooASSISTANT PROFESSOR

  • Websitermsd.dgist.ac.kr 링크이동
  • E-mailjgkim@dgist.ac.kr
  • Phone+82.53.785.6536
  • OfficeE2-608
  • LabBE2-621
professor_profile

RESEARCH AREA

  • Reaction mechanism
  • Protein structural dynamics
  • Solution-phase reaction dynamics
  • Time-resolved x-ray scattering

ACADEMIC & CAREER EXPERIENCE

ACADEMIC Ph. D., KAIST, Korea
Postdoctoral researcher at KAIST
CAREER Research Fellow at Institute for Basic Science (IBS)

Our Researches

The most intuitive approach to unveiling reaction mechanisms is real-time tracking of the three-dimensional structure of molecules involved in a chemical reaction. We utilize time-resolved x-ray scattering to visualize the structural changes of molecules, capturing a dynamic “molecular movie”, which allows us to identify precise reaction pathways and mechanisms. This method is not limited to small molecules but can also be applied to macromolecules such as proteins, enabling real-time tracking of structural changes in proteins during biologically-relevant reactions. Our ultimate goal is to provide fundamental information on the mechanism of various chemical reactions, which can be valuable for optimizing catalytic efficiency and controlling reaction products. Furthermore, by elucidating the correlation between protein structure and function, we can also gain insights into various biological phenomena and diseases caused by abnormal protein interactions.

Representative Publications

2020 “Mapping the emergence of molecular vibrations mediating bond formation”
J. G. Kim, S. Nozawa, H. Kim, E. H. Choi, T. Sato, T. W. Kim, K. H. Kim, H. Ki, J. Kim, M. Choi, Y. Lee, J. Heo, K. Y. Oang, K. Ichiyanagi, R. Fukaya, J. H. Lee, J. Park, I. Eom, S. H. Chun, S. Kim, M. Kim, T. Katayama, T. Togashi, S. Owada, M. Yabashi, S. J. Lee, S. Lee, C. W. Ahn, D.-S. Ahn, J. Moon, S. Choi, J. Kim, T. Joo, J. Kim, S. Adachi, H. Ihee*
Nature 2020, 582, 520
2015 “Direct observation of bond formation in solution with femtosecond X-ray scattering”
K. H. Kim#, J. G. Kim#, S. Nozawa#, T. Sato#, K. Y. Oang, T. W. Kim, H. Ki, J. Jo, S. Park, C. Song, T. Sato, K. Ogawa, T. Togashi, K. Tono, M. Yabashi, T. Ishikawa, J. Kim, R. Ryoo, J. Kim, H. Ihee*, S.-i. Adachi*
Nature 2015, 518, 385
2022 “Determining the charge distribution and the direction of bond cleavage with femtosecond anisotropic x-ray liquidography”
J. Heo#, J. G. Kim#, E. H. Choi, H. Ki, D.-S. Ahn, J. Kim, S. Lee, H. Ihee*
Nature Communications 2022, 13, 522
2021 “Ultrafast coherent motion and helix rearrangement of homodimeric hemoglobin visualized with femtosecond X-ray solution”
Y. Lee#, J. G. Kim#, S. J. Lee, S. Muniyappan, T. W. Kim, H. Ki, H. Kim, J. Jo, S. R. Yun, H. Lee, K. W. Lee, S. O. Kim, M. Cammarata, H. Ihee*
Nature Communications 2021, 12, 3677
2021 “Femtosecond X-ray liquidography visualizes wavepacket trajectories in multidimensional nuclear coordinates for a bimolecular reaction”
J. G. Kim, E. H. Choi, Y. Lee, H. Ihee*
Accounts of Chemical Research, 2021, 54, 1685
2015 “Protein structural dynamics revealed by time-resolved X-ray solution scattering”
J. G. Kim#, T. W. Kim#, J. Kim, H. Ihee*
Accounts of Chemical Research, 2015, 48(8), 2200
Back to list

Categories
Chemistry English Faculty Faculty & Research

Seo, Sangwon

Faculty & Research


Chemistry

Seo,SangwonASSISTANT PROFESSOR

  • WebsiteSSEO GROUP 링크이동
  • E-mailsangwon.seo@dgist.ac.kr
  • Phone+82.53.785.6535
  • OfficeE2-610
  • LabBE2-617
professor_profile

RESEARCH AREA

  • Organic Synthesis
  • Molecular Design
  • Base Metal Catalysis
  • Biocatalysis

ACADEMIC & CAREER EXPERIENCE

ACADEMIC Ph. D., University of Manchester, U. K.
CAREER Postdoctoral Research Associate, University of Oxford
Young Scientist Fellow, Institute for Basic Science

Our Researches

The fundamental principle of our research is to invent new reaction modes and unique catalytic systems for sustainable organic synthesis. We aim to achieve this in as an original way as possible, not only by harnessing our expertise in organic chemistry but also by interdisciplinary approaches involving organometallic, biological, and computational chemistry as additional tools. The main focus is placed on the development of cost-effective and atom-economical organic reactions that would address the environmental issues we currently face in chemical industries.

Representative Publications

2022 “Endo-Selective Intramolecular Alkyne Hydroamidation Enabled by NiH Catalysis Incorporating Alkenylnickel Isomerization”
Hoonchyl Choi, Xiang Lyu, Dongwook Kim, Sangwon Seo*, Sukbok Chang*
J. Am. Chem. Soc. 2022, 144, 10064
2022 “Photoinduced α-C–H Amination of Cyclic Amine Scaffolds Enabled by Polar-Radical Relay”
Wongyu Lee, Dongwook Kim, Sangwon Seo*, Sukbok Chang*
Angew Chem. Int. Ed. 2022, 61, e202202971
2021 “Merging NiH Catalysis and Inner-Sphere Metal-Nitrenoid Transfer for Hydroamidation of Alkynes”
Xiang Lyu, Jianbo Zhang, Dongwook Kim, Sangwon Seo*, Sukbok Chang*
J. Am. Chem. Soc. 2021, 143, 5867
2021 “Controlled Relay Process to Access N-Centered Radicals for Catalyst-Free Amidation of Aldehydes under Visible Light”
Wongyu Lee, Hyun Ji Jeon, Hoimin Jung, Dongwook Kim, Sangwon Seo*, Sukbok Chang*
Chem 2021, 7, 495
2020 “Ring-Opening Functionalizations of Unstrained Cyclic Amines Enabled by Difluorocarbene Transfer”
Youyoung Kim, Joon Heo, Dongwook Kim, Sukbok Chang*, Sangwon Seo*
Nat. Commun. 2020, 11, 4761.
Back to list

Categories
Chemistry English Faculty Faculty & Research

Hong, Seonki

Faculty & Research


Chemistry

Hong, SeonkiASSOCIATE PROFESSOR

professor_profile

RESEARCH AREA

  • Bio-inspired organic materials
  • Polymeric biomaterials
  • Surface biofunctionalization
  • In vitro bioassays

ACADEMIC & CAREER EXPERIENCE

ACADEMIC KAIST, Korea
Ph. D.
CAREER Massachusetts General Hospital, Harvard Medical School
Postdoctoral Researcher, 2015-2017

Our Researches

Catecholic/polyphenolic moieties are involved in various molecular interactions that mediate the adhesion, cohesion, coloration, and others of organic materials in nature. We design novel biomaterials by mimicking the unique chemical structures of these catecholic/polyphenolic biomaterials to address the current unmet needs in biomedical engineering. Specific research topics are listed below.
  • Multifunctional melanin-mimetic organic materials for biosensing
  • Adhesive bioink/biopigment system for bioprinting and biofabrication
  • Surface biofunctionalization of medical devices
  • Catecholic/polyphenolic nanomaterials for drug delivery and theranostics

Representative Publications

2022 “G-SNAP: A gelation-based single-step naked-eye assay platform mediated by biomarker-triggered enzymatic quinone tanning”
Jisoo Lee, Seonki Hong*
Sens. Actuators B: Chem, 360, 131664 (2022)
2022 “Dialysis-derived urchin-like supramolecular assembly of tannic acid and paclitaxel with high porosity”
Jiyeon Kim, Chanuk Choi, Seonki Hong*
Nanoscale, 14, 1363-1369 (2022)
2021 “Rapid and simple single-chamber nucleic acid detection system prepared through nature-inspired surface engineering”
Jihyo Park, Sangwon Woo, Jiyeon Kim, Hakho Lee*, Yeong-Eun Yoo*, Seonki Hong*
Theranostics, 11(14), 6735-6745 (2021)
2020 “Nature-inspired adhesive catecholamines for highly concentrated colorimetric signal in spatial biomarker labeling”
Seunghwi Kim, Seonki Hong*
Adv Healthc Mater, 9, 2000540 (2020)
2020 “A nature-inspired protective coating on soft/wet biomaterials for SEM by aerobic oxidation of polyphenols”
Hong K. Park, Daiheon Lee, Haeshin Lee*, Seonki Hong*
Mater Horiz, 7, 1387-1396 (2020)
Back to list

Categories
Chemistry English Faculty Faculty & Research

Jung, Byunghyuck

Faculty & Research


Chemistry

Jung, ByunghyuckASSOCIATE PROFESSOR

professor_profile

RESEARCH AREA

  • Catalytic Asymmetric Synthesis
  • Synthetic Methodologies
  • Synthesis of Natural Products and Drugs

ACADEMIC & CAREER EXPERIENCE

ACADEMIC KAIST, Korea
Ph. D.
CAREER Senior Engineer at Samsung Electro-Mechanics
Postdoctoral researcher at KAIST
Postdoctoral researcher at Boston College

Our Researches

Asymmetric Organic Synthesis and Drug Synthesis Laboratory(비대칭 유기합성 및 의약품 합성 연구실)
– Most of drugs, including Remdesivir® as a potential candidate for COVID-19, have chiral carbon-centers and Thalidomide-scandal had brought the importance of stereoselective synthesis of drugs. In this sense, we pursue the development of practical and efficient asymmetric reactions to apply for the lab-scale or bulk-scale synthesis of chiral drugs. To realize that, we focus on 1) the design and the synthesis of novel chiral catalysts, 2) the development of practical reagents, and 3) the development of novel methodology for C-C, C-O, C-N, or C-B bond formations.

Representative Publications

2022 “Synthesis of Alkynamides through Reaction of Alkyl- or Aryl-Substituted Alkynylaluminums with Isocyanates”
Cho, S.; Lee, Y.; Lee, K.; Lee, H.; Lee, Y.; Jung, B.
Org. Biomol. Chem. 2022, 20, 139-151.
2021 “Pd-Catalyzed Regio- and Stereoselective sp3 C-H Arylation of Primary Aliphatic Amines: Mechanistic Studies and Synthetic Applications”
Ha, H.; Choi, H. J.; Park, H.; Gwon, Y.; Lee, J.; Kwak, J.*; Kim, M.*; Jung, B.*
Eur. J. Org. Chem. 2021, 1136-1145
2020 “Stereoselective Formal Hydroamidation of Si-Substituted Arylacetylenes with DIBAL-H and Isocyanates: Synthesis of (E)- and (Z)-α-Silyl-α,β-Unsaturated Amides”
Lee, H.; Cho, S.; Lee, Y.*; Jung, B.*
J. Org. Chem. 2020, 85, 12024-12035.
2019 “Synthetic Strategies for (-)-Cannabidiol and Its Structural Analogs”
Jung, B.*; Lee, J. K.; Kim, J.; Kang, E. K.; Hans, S. Y.; Lee, H.-Y.; Choi, I. S.*
Chem. Asian. J. 2019, 3749-3762.
2018 “Cu(I)-Catalyzed Enantioselective Alkyl 1,4-Additions to (E)-Nitroalkenes and Cyclic Enones with Phosphino-Oxazoline Ligands”
Shin, M.; Gu, M.; Lim, S. S.; Kim, M.-J.; Lee, J.-H.; Jin, H.-G.; Jang, Y. H.; Jung, B.*
Eur. J. Org. Chem. 2018, 3122–3130.
Back to list

Categories
Chemistry English Faculty Faculty & Research

Jeong, Nak Cheon

Faculty & Research


Chemistry

Jeong, Nak CheonPROFESSOR

  • Websitenclab링크
  • E-mailnc@dgist.ac.kr
  • Phone +82.53.785.6513
  • OfficeE2-412
  • Lab E2-421
professor_profile

RESEARCH AREA

  • Inorganic Chemistry
  • Metal-Organic Framework
  • Nanoporous Materials
  • Electron Transport/Ion Transport

ACADEMIC & CAREER EXPERIENCE

ACADEMIC Sogang University, Korea
Ph. D.
CAREER Northwestern University, US
Postdoctoral Fellow

Our Researches

  1. Metal-Organic Frameworks (MOFs)

    The NC-Jeong group is developing the chemical science and applications using the precise assembly of materials by the molecular building block approach. For this, we use supramolecular chemistry where molecular building blocks (organic molecules, inorganic clusters and complexes, proteins, peptides, and dendrimers) are linked into extended frameworks with strong bonds. This chemistry allows us to translate the high functionality of molecules into solids without losing the robustness needed for making useful materials and the dynamics and molecular flexibility required for highly functional materials. Thus, in our group new materials are created by ‘stitching’ metal-ions and metal complexes with organic linkers to make extended porous frameworks called metal-organic frameworks (MOFs). These are all new classes of porous crystals studied for their applications to clean energy storage and generation, clean water generation and delivery, supercapacitors, thermal batteries, ion-conductivity, and electronic conductivity.

  2. Chemical Science

    Our research is focused on using metal complexes and metal-oxide clusters as building units in the synthesis of MOFs. These inorganic units are copolymerized with organic linkers to make MOFs and related porous crystals. An important direction pertains to exposing metal coordination sites within the pores. Here, terminal ligands are found on the metal connectors at axial position. These ligands can be removed with full preservation of the structure, thereby leading to open metal sites in low coordinated metals. The electronic and steric nature of these open metal sites makes them ideal for studying chemical science, for examples, discovering weak coordination bonding, coordination exchange, non-radiative thermal relaxation phenomena, and hydrogen bonding.

  3. Membrane & Film Technology

    Increase in the world’s population has increased demand for both eco-friendly energy sources and high-quality drinking water. The desalination of seawater is considered as a viable option to produce large amounts of clean drinking water, however, current processes to achieve this large amounts consumption of energy and the porous materials used to filter seawater lack fine control over pore-size. Ion-exchange membranes will be a promising key materials in the process of seawater desalination. Proton-exchange membrane fuel cells have shown the potential to reduce the environmental impact in energy consumption, but current technology for the applications are limited by high costs and short lifetimes of membranes. In our group, we seek to apply supramolecular chemistry to solve these issues. Currently, we are investigating a series of hybrid polymeric porous membranes and films, alongside chemically interlocked inorganic polymers, which incorporate various redox-active building blocks, to produce the next generation of water desalination, fuel-cell membranes, and electronic film devices.

  4. Ion Transport System

    An ultimate goal in proton-exchange membrane fuel cells, lithium ion batteries, and supercapacitors is to find better ionic conducting systems. MOFs can be considered as ideal systems for these applications because their potentially high ion transport abilities. Meanwhile, porous carbon materials have been used for commercial lithium ion batteries and supercapacitors that operate by storing charge on electrochemical double layers. By contrast, pseudocapacitors typically made from metal oxides can store charge by redox reactions. These classes of supercapacitor have both merits and demerits: carbon-based materials operate at very high charge/discharge rate with long lifecycle but have low capacitance, while metal oxide materials have high capacitance but their redox reactions lead to low lifecycle. We are working on ways of bridging the gap separating these two classes, using MOFs.

Representative Publications

2019 “Coordinative Reduction of Metal Nodes Enhances the Hydrolytic Stability of a Paddlewheel Metal−Organic Framework”
Dahae Song, Jinhee Bae, Hoon Ji, Min-Bum Kim, Youn-Sang Bae, Kyo Sung Park, Dohyun Moon,* and Nak Cheon Jeong*
J. Am. Chem. Soc. 2019, 141, 7853- 7864.
*Selected as a cover article
2018 “Metal Coordination and Metal Activation Abilities of Commonly Unreactive Chloromethanes toward Metal–Organic Frameworks”
Jinhee Bae, Eun Ji Lee, and Nak Cheon Jeong*
Chem. Commun. 2018, 54, 6458-6471.
*Invited as a feature article in the issue of Emerging Investigators 2018; *Selected as the front cover article
2017 “Multiple Coordination Exchanges for Room-Temperature Activation of Open-Metal Sites in Metal−Organic Frameworks”
Jinhee Bae, Jae Sun Choi, Sunhyun Hwang, Won Seok Yun, Dahae Song, JaeDong Lee, and Nak Cheon Jeong*
ACS Appl. Mater. Interfaces 2017, 9, 24743-24752.
2015 “A Chemical Route to Activation of Open Metal Sites in the Copper-Based Metal-Organic Framework Materials HKUST-1 and Cu-MOF-2”
Hong Ki Kim, Won Seok Yun, Min-Bum Kim, Jeung Yoon Kim, Youn-Sang Bae, JaeDong Lee, Nak Cheon Jeong*
J. Am. Chem. Soc. 2015, 137, 10009-10015.
2014 “A Metal-Organic Framework-Based Material for Electrochemical Sensing of Carbon Dioxide”
Jeremiah J. Gassensmith,† Jeung Yoon Kim,† James M. Holcroft, Omar K. Farha,* J. Fraser Stoddart,* Joseph T. Hupp, Nak Cheon Jeong* (†Equal contribution)
J. Am. Chem. Soc. 2014, 136, 8277-8282.
2012 “Effective Panchromatic Sensitization of Electrochemical Solar Cells: Strategy and Organizational Rules for Spatial Separation of Complementary Light Harvesters on High-Area Photoelectrodes”
Nak Cheon Jeong,* Ho-Jin Son, Chaiya Prasittichai, Chang Yeon Lee, Rebecca A. Jensen, Omar K. Farha, Joseph T. Hupp*
J. Am. Chem. Soc. 2012, 134, 19820-19827.
2012 “Coordination-Chemistry Control of Proton Conductivity in the Iconic Metal-Organic Framework Material HKUST-1”
Nak Cheon Jeong, Bappaditya Samanta, Chang Yeon Lee, Omar K. Farha, Joseph T. Hupp*
J. Am. Chem. Soc. 2012, 134, 51-54.
Back to list

Categories
Chemistry English Faculty Faculty & Research

lee, Sungi

Faculty & Research


Chemistry

Lee, SunggiASSOCIATE PROFESSOR

professor_profile

RESEARCH AREA

  • Organic Synthesis
  • Reaction and Catalyst Development
  • Material Development

ACADEMIC & CAREER EXPERIENCE

ACADEMIC Ph. D., KAIST, Korea
CAREER 2014~2019: Post-Doctoral Fellow, Max-Planck-Institute für Kohlenforschung, Germany
2012~2014: Post-Doctoral Fellow, Chemistry Department Boston College, USA
2009~2012: Research Scientist, SK Innovation Global Technology, Korea

Our Researches

  • Catalyst development

    Organo- and Transitionmetal catalyzed reactions based on structure design

  • Control of selectivity

    Control regio, diastereo, and enantioselectivities

  • Synthesis

    All the organic molecules anywhere in the world

Representative Publications

2018 “Confined acids catalyze asymmetric single aldolizations of acetaldehyde enolates”
Schreyer, L.; Kaib, P. S. J.; Wakchaure, V.; Obradors, C.; Properzi, R.; Lee, S.
List, B. Science 2018, 362, 216-219.
2018 “Can a Ketone be More Reactive than an Aldehyde: Catalytic Asymmetric Synthesis of Substituted Tetrahydrofurans”
Lee, S.; Bae, H. Y.
List, B. Angew. Chem. Int. Ed. 2018, 57, 12162-12166.
2018 “Approaching Sub-ppm Level Asymmetric Organocatalysis of a Highly Challenging and Scalable Carbon–Carbon Bond Forming Reaction”
Bae, H. Y.; Höfler, D.; Kaib, P. S. J.; Kasaplar, P.; De, C.; Döhring, D.; Lee, S.; Kaupmees, K.; Leito, I.
List, B. Nat. Chem. 2018, 10, 888-894.
2018 “The Activation of Olefins via Asymmetric Brønsted Acid Catalysis”
Tsuji, N.; Kennemur, J. L.; Buyck, T.; Lee, S.; Prévost, S.; Kaib, P. S. J.; Bykov, D.; Farès, C.
List, B. Science 2018, 359, 1501-1505.
2018 “N-Triflylphosphorimidoyl Trichloride: A Versatile Reagent for the Synthesis of Strong Chiral Brønsted Acids.”
Lee, S.; Kaib. P. S. J.
List, B. Synlett 2017, 28, 1478-1480.
2018 “Asymmetric Catalysis via Cyclic, Aliphatic Oxocarbenium Ions.”
Lee, S.; Kaib. P. S. J.
List, B. J. Am. Chem. Soc. 2017, 139, 2156-2159.
Back to list

Categories
Chemistry English Faculty Faculty & Research

Sung, Jooyoung

Faculty & Research


Chemistry

Sung, JooyoungASSISTANT PROFESSOR

  • WebsiteFemtoLab 링크이동
  • E-mailjooyoung@dgist.ac.kr
  • Phone+82.53.785.6533
  • OfficeE2-212
  • LabE2-218
professor_profile

RESEARCH AREA

  • Nanostructured Semiconductor Materials
  • Advanced Organic Materials
  • Optoelectronic Properties
  • Time/Space-resolved Spectroscopy

ACADEMIC & CAREER EXPERIENCE

ACADEMIC Ph. D., Yonsei University, Korea
CAREER Postdoctoral researcher at University of Oxford, UK (2016-2017)
Postdoctoral researcher at Cavendish Laboratory, University of Cambridge, UK (2017-2021)

Our Researches

Understanding photophyisical properties of various energy materials is the first step toward developing and utilizing novel energy materials. We develop and utilize the most advanced spectroscopy techniques to elucidate how charge carriers/excitons/ions behave in new energy materials such as organic semiconductors, perovskites, quantum dots etc. By achieving femtosecond time resolution and nanoscale spatial resolution, we successfully provide unprecedented optical and electronic properties of next generation energy materials.

Representative Publications

2022 “ltrafast Exciton Transport at Early Times in Quantum Dot Solid”
Zhilong Zhang, Jooyoung Sung*, Daniel Toolan, Sanyang Han, Raj Pandya, Michael Weir, James Xiao, Simon Dowland, Mengxia Liu, Anthony Ryan, Richard Jones, Shujuan Huang, Akshay Rao*
Nature Materials, (2022), (doi.org/10.1038/s41563-022-01204-6)
2021 “Non-Equilibrium Carrier Transport in Strongly Coupled Quantum Dot Solids and Heterostructures”
Mengxia Liu, Sachin Dev Verma, Zhilong Zhang, Jooyoung Sung*, Akshay Rao*
Nano Letters, 21, (21), 8945-8951 (2021)
2020 “Long-range ballistic propagation of carriers in methylammonium lead iodide perovskite thin films”
Jooyoung Sung, Christoph Schnedermann, Limeng Ni, Aditya Sadhanala, Richard YS Chen, Changsoon Cho, Lee Priest, Jong Min Lim, Hyun-Kyung Kim, Bartomeu Monserrat, Philipp Kukura, Akshay Rao
Nature Physics, 16, 2, 171-176 (2020)
2016 “Direct observation of excimer-mediated intramolecular electron transfer in a cofacially-stacked perylene bisimide pair”
Jooyoung Sung, Agnieszka Nowak-Król, Felix Schlosser, Benjamin Fimmel, Woojae Kim, Dongho Kim, Frank Würthner
Journal of the American Chemical Society, 138, 29, 9029-9032 (2016)
2015 “Direct observation of ultrafast coherent exciton dynamics in helical π-stacks of self-assembled perylene bisimides”
Jooyoung Sung, Pyosang Kim, Benjamin Fimmel, Frank Würthner, Dongho Kim
Nature Communications, 6, 1, 1-7 (2015)
Back to list

Categories
Chemistry English Faculty Faculty & Research

Seo, Daeha

Faculty & Research


Chemistry

Seo, DaehaASSOCIATE PROFESSOR

  • Websitesmall.dgist.ac.kr 링크이동
  • E-maillivewire@dgist.ac.kr
  • Phone+82.53.785.6525
  • OfficeE2-509
  • LabBE2-519
professor_profile

RESEARCH AREA

  • Nano-Bio-Chemistry
  • Single Molecule Biophysics

ACADEMIC & CAREER EXPERIENCE

ACADEMIC Ph. D., KAIST, Korea
CAREER Postdoctoral researcher at KAIST
Postdoctoral researcher at U.C. San Francisco
Postdoctoral researcher at U.C. Berkeley and LBNL

Our Researches

By combining chemical, biological, and physical tools, we are studying how membrane receptor react against environmental change, linked to cellular signaling and disease at single molecule level. To establish the platform technologies enabling simultaneous imaging, tracking and extracting bio-physical parameters, we are developing various chemical, optical, computational technology such as nanoparticle chemistry, super-resolution microscope, and machine learning algorithms.

Representative Publications

2022 “Combinatorial selective synthesis and excitation experiments for quantitative analysis of the effects of Au on a semiconductorphotocatalyst”
Yongdeok Ahn, Jiseong Park, Minsoo Park, Siwoo Jin, Woohyun Jo, Jeongho Kim, Seung Hwan Cho, Daeha Seo,*
Chem 2022, 8, 2485
2022 “TwoGPSesin a ball: deciphering the endosomal tug-of-war using plasmonic dark-field STORM”
Siwoo Jin, Jiseong Park, WonheeJohn Lee, Yongdeok Ahn, Youngchan Park, Minsoo Park, Inchan Hwang, Kwanyong Seo, Daeha Seo,*
J. Am. Chem. Soc. Au 2022, 2, 7, 1596
2019 “Artificial Control of Cell Signaling Using a Photocleavable Cobalt(III)-Nitrosyl Complex”
Sangwon Shin#, Jisu Choe#, Youngchan Park#, Donghyun Jeong, Hyunjoon Song, Youngmin You*, Daeha Seo*, Jaeheung Cho*
Angew. Chem. Int. Ed. 2019, 131, 10232
2018 “Single-Molecule Rotation for EGFR Conformational Dynamics in Live Cells”
Youngchan Park, Sangwon Shin,H yeonggyu Jin, Jiseong Park, Yeonki Hong, Jaemin Choi, Byunghyuck Jung*, Hyunjoon Song*, Daeha Seo*
J. Am. Chem. Soc. 2018, 140, 15161
2016 “AMechanogeneticToolkit for Interrogating Cell Signaling in Space and Time”
Daeha Seo, Kaden M. Southard, Ji-wook Kim, Hyunjung Lee, Justin Farlow, Jung-uk Lee, David Litt, Thomas Haas, Jinwoo Cheon, A. Paul Alivisatos, Zev J. Gartner, Young-wook Jun
Cell, 2016, 165, 1507.
Back to list

Categories
Chemistry English Faculty Faculty & Research

Park, Jinhee

Faculty & Research


Chemistry

Park, JinheeASSOCIATE PROFESSOR

professor_profile

RESEARCH AREA

  • Organic-Inorganic Hybrid Materials
  • Metal-Organic Polyheda/Metal-Organic Frameworks
  • Porous Polymer Networks

ACADEMIC & CAREER EXPERIENCE

ACADEMIC Ph. D., Texas A&M University, USA
CAREER Senior Researcher, Korea Electrotechnology Research Institute, 2013-2015
Postdoctoral Researcher, Texas A&M University, 2013

Our Researches

  1. Metal-Organic Frameworks

    Metal-organic frameworks (MOFs) as a class of well-ordered porous crystalline materials have attracted continuous interests owing to their structural and functional diversity as well as high porosity and large surface area. The structure, pore size, and surface functionalities of MOFs can be designed and finely tuned by judicious choices of building blocks such as metal-containing nodes and organic linkers. Introduction of functionalized pores into MOFs can lead to their diverse applications, such as gas storage, separation, catalysis, and drug delivery.

  2. Metal-Organic Polygons/Polyhedra

    Among such self-assembled structures, diverse metal-organic polygons/polyhedra (MOPs) have been designed and prepared based on inspirations drawn from geometric entities such as Archimedean/Platonic solids and biological units with multiple interaction sites. We are especially interested in stimuli-responsive MOPs due to their potential applications in diverse fields including sensors, adaptable surface coatings and controllable molecular machines. The designability and intrinsic porosity of metal-organic polyhedra/polygons (MOPs) present an opportunity for developing new types of stimuli-responsive materials.

Representative Publications

2022 “Multi-Stimuli-Engendered Radical-Anionic Metal-Organic Frameworks: Visualization of Structural Transformation upon Radical Formation”
Park. S.; Lee. J.; Jeong. H.; Bae. J.; Kang. J*; Moon. D.*; Park, J.*
Chem. 2022. 10.1016/j.chempr.2022.03.023
2020 “Synthesis and Photocatalytic Properties of Titanium-Porphyrinic Aerogels
Keum, Y.; Kim, B.; Byun, A.; Park, J.*
Angew. Chem. Int. Ed. 2020, 59, 21591-21596.
2021 “Metal-Organic Frameworks as a Versatile Platform for Radionuclide Management”
Jin, K.; Lee, B.; Park, J.*
Coord. Chem. Rev. 2021, 427, 213473.
2020 “Microscopic and Mesoscopic Dual-Post-Synthetic Modification of Metal-Organic Frameworks”
Lee, B.; Moon, D.*; Park, J.*
Angew. Chem. Int. Ed. 2020, 59, 13793-13799.
2018 “Titanium-Carboxylate Metal-Organic Framework Based on an Unprecedented Ti-oxo Chain Cluster”
Keum, Y.; Park, S.; Chen, Y.-P.; Park, J.*
Angew. Chem. Int. Ed. 2018, 57, 14852-14856.
Back to list

Categories
Chemistry English Faculty Faculty & Research

Kim, Seongkyun

Faculty & Research


Chemistry

Kim, Seong KyunASSOCIATE PROFESSOR

professor_profile

RESEARCH AREA

  • Inorganic & Organometallic Chemistry
  • Homogeneous/Hetereogeneous Catalysis
  • Biomass Materials
  • Functional Polymerse & Engineering Plastics

ACADEMIC & CAREER EXPERIENCE

ACADEMIC Department of Chemistry, KAIST, KOREA
B.S., M.S. & Ph. D.
CAREER Assistant & Associate Professor, Undergraduate studies, DGIST
Senior Researcher, SK Innovation
Senior Researcher, SamsungCheil industries
Postdoctoral Researcher at UCLA & KAIST

Our Researches

Water Treatment/Desalination/Purification Materials
Catalytic Degradation and Upcycling of Fossil-Based Plastics
Cellulose/Lignin Biomass, Waste Upcycling

Representative Publications

2023 “An Easily Scalable, Durable, and Highly Efficient Three-Dimensional Solar Evaporator Inspired by a Rice Paddy Field”
H Lim & SK Kim
Desalination, 2023, 548 116251.
2022 “Environmentally safe and renewable solar vapor generation device based on Prussian blue nanoparticles immobilized on cellulose nanofibers”
H Lim, M Kim, J Yoo, D Lee, M Lee, B Na, SK Kim
Desalination, 2022, 524, 115477.
2019 “Hands-On Experiment to Verify Consistency from Bulk Density to Atomic and Ionic Radii with Lumps of Metals and Ionic Compounds”
SK Kim, S-H Paik
J. Chem. Educ. 2019, 96, 2271-2278.
2015 “Cyclopenta[b]fluorenyl transition metal compound, catalyst composition containing the same, and method of preparing ethylene homopolymer or copolymer of ethylene and α-olefin using the same”
US Patent 9,120,884. 2015
Back to list